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This exceptionally high enzyme stability of the bicyclic and tricyclic GLP-1 analogs would be of interest in achieving a long-acting in vivo activity and molecular imaging of pancreatic -cells via the GLP-1 receptor (vide infra)

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This receptor consists of 463 amino acids, belongs to the GPCR family, and has been cloned and confirmed in multiple human tissues, including the brain, lungs, and heart

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It has no approved drug label, no compounding pharmacy availability, and no recognized dietary supplement status under DSHEA