In 2024 consensus-based guidance was formulated by representatives from the American Society of Anesthesiologists (ASA), the American Gastrointestinal Association (AGA), the American Society for Metabolic and Bariatric Surgery (ASMBS), the International Society of Perioperative Care of Patients with Obesity (ISPCOP), and the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) [19], according to which, use of GLP-1RAs and the management in the perioperative period should be based on shared decision-making of the patient, the anaesthetist, the prescribing care team, and the surgeon [19, 20]
Increased hepatic fat accumulation results in heightened lipotoxicity, adipose tissue inflammation, impaired mitochondrial function and ERS
Reduced water availability, together with an increasingly negative soil osmotic potential, profoundly reconfigures the physicochemical gradients of the rhizosphere, simultaneously affecting water diffusion, nutrient mobility, soil aggregate stability, and microbial activity (Dao et al
Many patients on weight loss programs also experience a natural drop in blood pressure as they lose weight
10.1208/s12248-011-9300-y 226 SiL.ZhangL.XingS.FangP.TianX.LiuX.et al (2023)
Concerns over undernutrition, particularly loss of lean body mass, due to low protein intake is consistent with previous publications [7,12,13]