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Relative to GLP-1RGIPR co-agonism, GLP-1GIPLani similarly decreased liver mass (Fig

These exclusions limit generalizability to real-world populations that are on polypharmacy

Some patients find that IV hydration therapy helps manage the dehydration and fatigue that can accompany the early adjustment period, particularly if nausea makes oral hydration challenging

The strongest evidence right now is in knee osteoarthritis (the STEP-9 trial) and rheumatoid arthritis (the UCLA cohort), with rapidly growing data in psoriatic arthritis and lupus

Expect requirements like documented BMI thresholds, proof of failed previous weight loss interventions, and mandatory comorbidity diagnoses before coverage kicks inif it kicks in at all

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