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Individuals motivated to make lifestyle changes such as diet and exercise

Patients who don't make these changes will not see that same dramatic weight loss

GLP-1 medications activate receptors in brain reward circuits that overlap with addiction pathways

Animals developed persistent esophagitis with hemorrhagic lesions, thinned epithelium, and chronically reduced sphincter pressures lasting up to 20 months

K.WongS

This review further highlights the importance of considering PPAT-prostate interorgan communication as a critical component in prostate carcinogenesis, particularly given the key role that the PPAT can have in modulating the TME towards fuelling cancer development, which can be exacerbated by the influence of obesogenic EDCs Fig