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Tregs are responsible for maintaining immune homeostasis by suppressing overactive immune responses, preventing autoimmune reactions, and ensuring tolerance to self-antigens [321]

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This may be confirmed by recent studies which show that thiamine and its derivatives participate in the modulation of protein expression through post-translational modifications

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10.1093/ajcn/nqaa447 12 DaiW.BaiZ.Ting-tingH

and protect against toxicity from cisplatin