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Glucocorticoids decrease the production of glucagon-like peptide-1 at the transcriptional level in intestinal L-cells

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Allain, F., Minogianis, E

Propranolol and Verapamil, both of which experience substantial first-pass metabolism, contributing to relatively low oral bioavailability

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There were also limited interactions between GH5 subunit and helix 8 of the receptor (E392 GH5 , N440 8.47b and G441 8.48b )