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Patients should contact their GP if they experience significant deterioration in blood glucose control (persistent readings above 15 mmol/L, symptoms of hyperglycaemia such as excessive thirst or urination), unexplained weight changes, or any concerning symptoms after stopping treatment

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P = 0.044), whereas there was reduced HDAC2 protein activity in PBMCs ( P 0.05)

Linearity of Calibration Curves Linearity for the calibration curve of each marker compound was observed in the range of 0.41.4 g/ml with the regression equations for the marker compounds as given below: the regression equation for diosgenin was Y = 1527.8 X + 65.653 ( R 2 = 0.9955)