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Pancreatic Acinar Metaplasia (Figures 164 and 165) Pathogenesis Islands of pancreatic tissue localized within the hepatic parenchyma are rare spontaneous occurrences in rats but have been reported following prolonged exposures to polychlorinated biphenyls (Kimbrough 1973

B9 (folate) : Essential for DNA synthesis and especially critical in pregnancy to support normal fetal development and reduce neural tube defect risk

(1994) Is the flavin-deficient red blood cell common in Maremma, Italy, an important defense against malaria in this area

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Similarly, in NASH models, prophylactic Lip-1 supplementation significantly reduces hepatic steatosis and improves liver histology ( -Tocopherol, also known as vitamin E, is a potent natural antioxidant that also functions as a ferroptosis inhibitor, effectively attenuating cellular lipid peroxidation and inhibiting ferroptosis (62)