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A 2025 Nature Communications paper mapped the binding to the disordered transactivation domain of p53, adding structural detail to how FOXO4-DRI engages its target

Glutathione plays an essential role in protecting both the mother and the developing baby from the oxidative stress that naturally occurs during pregnancy

Patients should be educated about the warning signs of pancreatitis, including severe, persistent abdominal pain that may radiate to the back, particularly when accompanied by nausea and vomiting

Active malignancy warrants avoidance as discussed above

doi: 10.5653/cerm.2020.04084 26 AlahmarATCalogeroAESenguptaPDuttaS

The RMSD plot of AKT1 bound the ligand 1,3,4,5-Tetrahydroxycyclohexanecarboxylic acid (PubChem Id: 1064) presented in Fig