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Noticeably, a major limitation of the current models utilizing Western diets, not employing micronutrient deficiency or abnormally high amounts of cholesterol, is the absence of progressive, advanced hepatic fibrosis [129]

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[Google Scholar]) suggesting that altered fecal bile acid metabolism may also be closely linked to ulcerative colitis

The molecular and structural/functional changes translate to (1) Tubular atrophy, podocyte hypertrophy, glomerulosclerosis, and microvascular rarefaction and (2) glomerular basement membrane thickening, nephrosclerosis, and extracellular matrix accumulation, respectively [84]

The contrast between diabetes and obesity coverage highlights a broader tension within healthcare systems, where evidence-based therapies are not always matched by equitable access