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Most researchers focus on obvious discoloration as the primary degradation signal, but that's a late-stage marker

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L-Arginine HCL is preferred in many supplement formulations due to its higher solubility and stability

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As discussed earlier, Koeth et al.'s study on gut microbiota-induced TMAO in stable patients undergoing cardiac evaluation showed significant dose-dependent associations between plasma L-carnitine levels and risks of coronary artery disease, peripheral artery disease, and overall CVD after correction for common CVD risk factors [18]