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Patients with MS often exhibit symptoms such as motor deficits, muscle weakness, sensory abnormalities, cognitive decline, and psychiatric abnormalities, which significantly affect the quality of life (Sturm et al., 2014)

Prenatal androgenization of female mice programs an increase in firing activity of gonadotropin-releasing hormone (GnRH) neurons that is reversed by metformin treatment in adulthood

Clinically, survivors with a history of mental illness or substance use are particularly prone to anxiety and depression symptoms post-infection (91)