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GI side effects and therapeutic effectiveness are both driven by the same mechanism of action

It refers to a medically supervised program using smaller, customized doses of semaglutide (the active ingredient in Ozempic and Wegovy)

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Moreover, in a post hoc analysis of the SURPASS-4 randomized clinical trial, tirzepatide decreased albuminuria and total estimated glomerular filtration rate (eGFR) slopes and nearly halved the risk of a pre-specified composite kidney endpoint (eGFR decline 40%, renal death, kidney failure or new-onset macroalbuminuria) in participants with T2DM and high cardiovascular risk when compared with insulin glargine

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