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The Journal of Sexual Medicine, 21 (Supplement_1), qdae001.148

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[1] [4] The large-scale randomised controlled trials, including the SUSTAIN and STEP programmes, were not specifically designed to assess sex hormone profiles as outcomes, and there is no signal of a direct oestrogen-lowering effect to date

Furthermore, the quantity and function of mitochondria can directly determine the oxidative phosphorylation efficiency of the skeletal muscle (143)