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Iron metabolism in thalassemia and sickle cell disease
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Shungu was then able to turn the pilot data gained into grants totaling almost $2 million
Hydrogen peroxide produced by neutrophils is used mainly by MPO which catalyzes oxidation reactions with the involvement of chlorine ions to produce hypochlorous acid (HOCl), hydroxyl radicals (OH ), singlet oxygen (O 2 1 ), and ozone (O 3 ) with strong bactericidal properties ( 2 - + H 2 O 2 OH - + OH - + O 2 ) and the Fenton reaction (H 2 O 2 + Fe 2+ Fe 3+ + OH - + OH - ) with the participation of pro-oxidant ions of transition metals (mostly Fe 2+ /Cu 2+ ) (51)