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Pattern 2: Step down to a lower dose For some patients particularly those who reached goal at the maximum dose a lower maintenance dose preserves most of the appetite suppression while reducing cost, side effects, and the burden of long-term use at maximum dose

The number of patients at the 4-milligram dose who discontinued treatment due to side effects was lower than the placebo group, which Skovronsky called "remarkable to see." Around 4% of patients on that dose stopped the drug due to side effects, compared with nearly 5% with the placebo

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Drink plenty of water, especially when using expectorants like guaifenesin

While the medication clears in 3 to 5 weeks, your brain's appetite regulation takes 2 to 8 weeks to recalibrate