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The primary endpoint for the liver disease study will be liver stiffness, a proxy for liver health thats less invasive than a biopsy, while the primary endpoint for the AUD study will be change in the number of heavy drinking days after 24 weeks of treatment

Physiology 10, 1042

ShanYTanSLinYLiaoSZhangBChenXet al

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Widely used for type 2 diabetes (T2D) and obesity, these agents offer benefits beyond glycemic control, including cardiovascular protection, with emerging evidence suggesting broader metabolic and possible neurocognitive effects