Abstract Oxalate homeostasis is maintained through a delicate balance between endogenous sources, exogenous supply and excretion from the body
95% CI, 0.47-0.68)
The absence of high-quality evidence means prescribers who recommend this combination are making an educated guess based on mechanistic reasoning rather than proven patient outcomes
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Moreover, with the Keytruda patent cliff looming (2028), Merck need a more rapid cash flow replacement that the GLP-1 field potentially offers