Intuitively, the inhibition of DNA damage repair by PARP may sensitize cancer cells to the oxidative stress induced by platinum-containing drugs
Preclinical models frequently demonstrate potentially promising effects of cannabinoids, but these findings are not reliably translated in clinical trials involving older adults (Gruber et al., 2016)
Although the new drug treatments have been shown to slow cognitive decline, the aggregate impact on health care use and costs is not yet known
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Two sites of ubiquitination have been found in the CBS structure [23], and it can be suspected that also this common modification of proteins plays a role in the regulation of CBS activity
FOXO3 also prevents pro-apoptotic BAX translocation to the mitochondria, hence protecting cells from apoptosis 100
