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This complex process means that conditions affecting the stomach or intestines can significantly impair B12 absorption, including pernicious anaemia, atrophic gastritis, previous gastric surgery, coeliac disease, Crohn's disease, and long-term use of certain medications (such as metformin, proton pump inhibitors, and H2 antagonists)

You can also take a pill every day without any major side effects, unlike an injection that you do not need as often

Older adults: B12 absorption can decline with age

In short: the cell-culture data establishes biological plausibility for hair-follicle effects

[86] Fortified foods [edit] Foods for which vitamin B 12 -fortified versions are available include breakfast cereals, plant-derived milk substitutes such as soy milk and oat milk, energy bars, and nutritional yeast

Ongoing studies are aimed at determining the potential relevance of NNMT inhibition to cognitive performance and neurological research