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The test lotion was composed of 2% (weight/weight [w/w]) GSSG (KYOWA HAKKO BIO CO., LTD., Tokyo, Japan), together with other ingredients, including 1,3-butylene glycol, mineral oil, 1,3-pentanediol, cetostearyl alcohol, self-emulsifiable glyceryl monostearate, ethylhexyl palmitate, polyethylene glycol monostearate, 1,3-hexandiol, 2-phenoxyethanol, carboxyvinyl polymer, polyacrylic acid amide, light liquid isoparaffin, polyoxyethylene lauryl ether, fragrance, and water (Table 1)

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If more than 4 days have passed, skip the missed dose and administer the next dose on the regularly scheduled day

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