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Due to their cost, however, coverage of GLP-1s for obesity treatment in Medicaid, ACA Marketplace plans, and most large employer firms remains limited, and GLP-1 coverage in Medicare for treatment of obesity is prohibited under current law

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The question of whether GLP-1 therapy qualifies as direct immunomodulation or whether the benefits are primarily mediated through weight loss and reduced adipose inflammation is still under active investigation

The MHRA has not licensed AOD 9604 as a medicinal product in the UK, and its status can be confirmed via the MHRA's product licence search

These effects occurred more frequently at higher doses and were generally consistent with the known side effect profile of incretin-based therapies