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The TYK2 allosteric inhibitor deucravacitinib achieves comparable IFN-I suppression, with Phase II trials confirming both safety and clinical improvement in SLE cohorts ( 4.6 Targeted T-cell therapy The abnormal activation of T-cells plays an important role in atherosclerosis associated with SLE (67)

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However, some patients may not achieve dramatic results, particularly if they miss doses or discontinue treatment prematurely

The effects of L-carnitine supplementation on physical performance and energy metabolism of endurance-trained athletes: A double-blind crossover field study