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Bowers (von Helden et al., 1995

In a United Kingdom-based study, the overall proportion of patients who discontinued GLP-1 RA therapy at 12 months was 45.2% and 64.7% at 24 months

To date, clinical trials have not shown a significantly higher risk profile for retatrutide compared to tirzepatide, provided that titration protocols are strictly followed in the research design

Clin Interv Aging 2009;4:367-77

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Market impact: intensifies competition with LillyDirect/NovoCare and retailers (Walmart), pushed Eli Lilly and Novo Nordisk shares lower and weighed on related obesitydrug stocks