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Overexpression of pregnancy-associated plasma protein-A in ovarian cancer cells promotes tumor growth in vivo

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Similar content being viewed by others Introduction Glutathione S -transferases (GSTs) constitute a family of detoxification enzymes that catalyze the conjugation of glutathione (GSH) with a variety of hydrophobic compounds, including drugs and their metabolites, to yield water-soluble derivatives that are excreted in urine or bile

Stolakis et al., 2010

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Peptides with hydrophobic motifs interact well with the lipid components of cell membranes, aiding their ability to penetrate cells 56