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Following the development of motor symptoms, cognitive dysfunctions progress due to the involvement of the atemporal cortex (Kalia 2018)

Solubility and Reconstitution Guidelines Due to its hydrophobic nature, the dihexa peptide requires careful preparation

Neither is FDA approved, and both have unsettled compounding status pending PCAC review

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Needle-like crystals in the mouse can be intracellular or extracellular and may be associated with intense eosinophilic epithelial cytoplasm and extracellular crystals of various sizes