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Menstrual changes and cycle disruptions have been reported by some female patients
Side effects are rare but may include vein irritation, dizziness, or mild nausea
Comprehensive evaluation helps identify contributing factors that need direct treatment
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Challenges Due to its well-established role in neural tube development, folic acid supplementation is recommended in clinical guidelines (US Preventive Services Task Force, American College of Obstetricians and Gynecologists, American Academy of Family Physicians, American Academy of Pediatrics, and the Center for Disease Control and Prevention) for those who are planning to or could become pregnant (Force et al., 2023)