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International Journal of Molecular Sciences 2018 Pickart & Margolina Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data A review examining the copper-binding tripeptide and cellular pathways associated with it in the published gene-expression and biochemical literature

10.1093/ibd/izz328 118

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Furthermore, PGC-1 suppresses the transport of NF-B p65 from the cytoplasm to the nucleus and the degradation of IB by regulating NF-B, thereby reducing A-induced neuronal death and inhibiting neuroinflammation, which in turn reduces mitochondrial damage and restores AD cognitive deficits (Zhang Y

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