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10.1071/rd22033 58 SjaardaL

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This low concentration of acetate is attributed to the intermolecular neutralization of the N-terminal amino group and the -amino group of lysine by carboxylate groups on the C-terminal or on the side chain of the aspartate and glutamate residues

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Overman MJ, Hu CY, Kopetz ES , Abbruzzese JL, Wolff RA, Chang GJ

252 In addition, SGI-110 has demonstrated the potential to reprogram CSCs into less tumorigenic states and enhance chemosensitivity, particularly in ovarian cancer models