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In it, a group of Japanese participants was randomized into either a tesamorelin group or a placebo group

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Off-gassing from carpeting may cause mast cell release in the case of sick building syndrome.[ref] Sodium benzoate, a common preservative, causes histamine release in people with allergies and asthma.[ref] Aspirin and other salicylates can cause histamine problems for some people, possibly through basophil activation.[ref] Polysorbate 80, a common food additive, causes histamine release.[ref] Polysorbate 80 is in most brands of pickles except organic pickles

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This observation in turn emphasises the importance that therapies aimed at modulating astrocyte reactivity will need to modulate specific molecules and specific aspects of reactivity in a disorder and context specific manner