Spondylodysplastic EDS (spEDS) is characterized by short stature (progressive in childhood), muscle hypotonia (ranging from severe congenital, to mild later-onset), and bowing of limbs Musculocontractural EDS (mcEDS) is characterized by congenital multiple contractures, characteristically adduction-flexion contractures and/or talipes equinovarus (clubfoot), characteristic craniofacial features, which are evident at birth or in early infancy, and skin features such as skin hyperextensibility, bruising, skin fragility with atrophic scars, and increased palmar wrinkling
This may include compounded semaglutide or other options based on clinical appropriateness
The intake gives the clinician useful context: goals, history, medication use, symptoms, and prior treatment experience before any injectable GLP-1 option is considered
Inject slowly without aspiration
Our results indicate that GLP1R mutations in humans lead to defective cell surface expression and impaired activation of the cAMP pathway, resulting in major defects in insulin secretion
Nasal Breathing (00:30:33) Tools 2 & 3: (Not) Touching Your Eyes