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They act through different tissue layers and carry different downtime and cost profiles

Jorsal A, Kistorp C, Holmager P, Tougaard RS, Nielsen R, Hanselmann A, et al

It has demonstrated oral stability in gastric juice and efficacy even at microgram or nanogram doses

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Several pro-angiogenic factors are known to drive vascular growth including vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), platelet-derived growth factor (PDGF), angiopoietins (Angs), hepatocyte growth factor (HGF), transforming growth factor- (TGF-), and matrix metalloproteinases (MMPs)

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