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Topical cosmetic use appears to be well tolerated for most individuals, though long-term systemic applications have not been fully studied

10.1002/syn.20362 Synapse 194 UeharaY.MinowaO.MoriC.ShiotaK.KunoJ.NodaT.et al (1995)

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Retrieved from National Library of Medicine

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1 mg cyanocobalamin, water for injections, sodium hydroxide for pH adjustment, sodium chloride, sodium dihydrogen phosphate 2 water At the beginning of the treatment, 1 ampoule of 1 ml vitamin B 12 Lichtenstein (corresponding to 1000 micrograms of cyanocobalamin) is administered twice a week in the first weeks after diagnosis