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States with Restrictions Some states have specific restrictions that affect telehealth prescribing for GLP-1 medications

At Cape Fear Physical Medicine and Rehab, we offer comprehensive weight management solutions, including the use of GLP-1 medications as part of our medically supervised programs

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For instance, exenatide, the first GLP-1-analogue developed, demonstrated to promote human monocyte differentiation into alternatively activated M2 macrophages, leading to an increase in anti-inflammatory cytokines such as IL-10 while significantly reducing pro-inflammatory cytokines, including IL-6, TNF- and IL-1 ( Furthermore, GLP-1 has been hypothesised to act as a mediator between innate and adaptive immune responses

These provisions were discussed in the CY 2012 OPPS/ASC final rule with comment period (76 FR 74191)