semaglutide 4 months I lost 25 pounds in on 4-5 months progress (~50lbs) :

[DOI] [PubMed] [Google Scholar] 147.Da Silva A.S., Munhoz T.D., Faria J.L.M., Vargas-Hrnandez G., Machado R.Z., Almeida T.C., Moresco R.N., Stefani L.M., Tinucci-Costa M

doi: 10.3389/fmicb.2025.1535356 Received 27 November 2024 Accepted 23 June 2025 Published 09 July 2025 Volume 16 - 2025 Edited by Zhangran Chen, Xiamen University, China Reviewed by Abbas Yadegar, Shahid Beheshti University of Medical Sciences, Iran Sourish Bhattacharya, Central Salt and Marine Chemicals Research Institute (CSIR), India Updates Copyright 2025 Zhu, Fu, Olovo, Xu, Wu, Wei, Jiang and Zheng

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Saxenda is specifically indicated for use in adults with obesity (with a body mass index BMIof 30 kg/m2 or greater) or overweight adults (a BMI of 27 kg/m2 or greater) who also have weight-related health conditions such as hypertension (high blood pressure), high cholesterol, or obstructive sleep apnea

While surgery can provide dramatic results, many people find that non-surgical treatments offer a fantastic, more accessible alternative for achieving firmer skin without the high cost and extended downtime

The cause of hepatic disease has been thought to be multifactorial in the setting of congestive hepatopathy from heart failure, malnutrition, previous or concomitant liver disease (i.e., infectious or autoimmune disease), and drug related liver injury, and possible liver ischemia from a mismatch between oxygen consumption and oxygen delivery to the liver (395-399)