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In this study, the results of flow cytometry, immunofluorescence staining, RT-qPCR and ELISA assays demonstrated that GLP-1RAs could drive macrophage polarization towards the M2 type, thereby inhibiting the continuous development of synovitis

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Previously, SHMT2 expression has been shown to be inversely associated with tumor-infiltrating lymphocytes in the tumor microenvironment of patients with lung adenocarcinoma, using TIMER and TISIDB online databases [73, 74]

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