Metabolic adaptation compounds the problem
Both hormones matter, but GLP-1 is likely the primary driver with GIP providing substantial enhancement
A licensed healthcare provider will factor in your weight, metabolic health, gastrointestinal history, tolerance, and goals
These may include nausea, decreased appetite, and digestive problems that usually improve over time 1,5 Staying hydrated, eating smaller meals, and avoiding high-fat foods might help make the transition smoother 4
On the other hand, whole foods aid digestion and balance your gut bacteria, supporting GLP-1 release
"The most notable benefits of GLP-1 receptor agonists for patients with diabetes or obesity are their ability to promote significant weight loss, reduction in appetite, and improvement in blood sugar control," says Dr