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While the animal model treated with PBS did not show any signs for ROS, high amounts of fluorescence signals in the tissue from the animal treated with NP4 were observed (Supplementary Fig

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1 Introduction Moderate elevations in circulating prolactin have been associated with favorable metabolic effects ( The global prevalence of overweight and obesity continues to rise and represents a major public health concern ( Several studies have demonstrated a positive association between serum prolactin levels and body mass index (BMI), suggesting a potential role for hyperprolactinemia in obesity pathophysiology ( 2 Prolactin: biological characteristics 2.1 Structure and secretion regulation Human mature prolactin is a 199-amino-acid polypeptide with an estimated molecular mass of ~23 kDa ( Prolactin-secreting cells (lactotrophs) in the anterior pituitary gland are the primary sources of prolactin synthesis and secretion

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