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As a novel method for identifying compounds that promote the release of the physiological agonist GLP-1, we have developed and optimized a GLP-1 secretion assay

In 2025, the company reported a modest +1.29% YoY revenue growth, shaped largely by its core portfolio: Keytruda ($31.68B) continues to dominate as one of the worlds top-selling oncology drugs with expanding indications, Gardasil/Gardasil 9 ($5.23B) remains a key growth driver in vaccines despite some demand fluctuations, and Januvia/Janumet ($2.54B) continues to decline as generic competition intensifies

Those on 10 mg achieved roughly 20 percent reduction

"Structure-function of the glucagon receptor family of G protein-coupled receptors, coupled to: the glucagon, GIP, GLP-1, and GLP-2 receptors"