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Additionally, direct neuronglia communication is facilitated through two-way calcium signaling, primarily via purinergic P2 receptors (notably P2X7) and gap junctions (39)

Macrophage dicer promotes tolerogenic apoptotic cell clearance and immune tolerance by inhibiting pentose phosphate pathway activity

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DOI:10.1093/ije/dyp337 [ Links ] 59

Subcutaneous and intraperitoneal routes give shorter circulating windows, with the compound clearing primarily through proteolytic degradation outside the GI tract rather than through renal or hepatic elimination as a single molecule