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42 Another RCT studied cyano-B12, 1500 g three times per day for 2 weeks (route not reported), in patients with seasonal affective disorder and found no improvements in either the B12 or the placebo group

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Patients dealing with chronic joint pain, post-surgical discomfort, or inflammatory conditions often notice reduced pain within the first 12 weeks of a protocol

In a dissenting comment, Sikiric and colleagues said that BPC-157 had been unjustly accused of potentially harmful effects. They pointed to a list of research findings that, in their view, rule out the possibility that the peptide causes cancer and other potential harms