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Translational studies will validate efficacy for precision therapies

The majority of this glucose is aerobically metabolized by astrocytes and, to a lesser extent, by oligodendrocytes, which ultimately release the metabolites (chiefly lactate) that fuel neurons though monocarboxylate transporters in glial-neuronal gap junctions [55]

A poorly dissolved reconstitution usually indicates either a problem with the BAC water (wrong type, contaminated) or a damaged lyocake from improper storage

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Preclinical studies using in vitro-transcribed mRNA chimeric antigen receptor T cells (IVT mRNA CAR T) have shown effective, targeted cytotoxicity against various hematologic cancers, including CLL, acute lymphoblastic leukemia, and acute myeloid leukemia (AML), as well as solid tumors including mesothelioma, ovarian cancer, breast cancer, neuroblastoma, glioblastoma (GBM), and melanoma