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Besides, Direct Peptide Reactivity Assay (DPRA) is the assay recommended by EURL ECVAM for skin sensitization testing

Arch Biochem Biophys (2021) 699:108765

There was some evidence of publication bias (Egger test, P = 0.94), but the trim-and-fill method indicated that this publication bias did not impact the estimate

To fully understand the differences in the mechanisms and long-term effects of GLP-1RAs on the retina, a combination of clinical trials and mechanism studies is necessary (85)

Indeed, SLC6A14 is overexpressed in colon, cervical, ER-positive breast, and pancreatic cancer cells and is associated with their proliferation 101,102,103,104