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doi: 10.1021/jp9628702

What it does is curb excess melanin production and when melanin goes unchecked, that's usually when dark spots and patchy tone start showing up

The RSSDI 2022 update keeps the same direction of travel [2]

The authors administered oral Dihexa to APP/PS1 transgenic mice (a standard amyloidopathy model of Alzheimers disease) and showed that brain AngIV levels were elevated relative to wild-type after Dihexa administration, that spatial learning and memory were restored on Morris water maze testing, that hippocampal neuronal density and synaptophysin protein expression were preserved, that astrocyte and microglial activation were reduced, and that pro-inflammatory cytokines (IL-1, TNF-) decreased while anti-inflammatory IL-10 increased

A comprehensive meta-analysis of observational cohort studies by Celsa et al

Tirzepatide increased force of contraction in the isolated human atrium