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These medications work by directly activating the GLP-1 receptor, amplifying the hormones effects
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Other medication-related exclusions included use of antiobesity medications, nutritional supplements or over-the-counter products for weight loss within 3 months prior to screening
Somani, S
Tirzepatides success as a dual GLP-1/GIP agonist is leading the way for next-generation multi-receptor agonists, and companies are exploring oral formulations pills to win over patients averse to injections
doi: 10.1016/j.jalz.2013.12.007 2 LaneCAHardyJSchottJM
Hartman ML, Sanyal AJ, Loomba R et al (2020) Effects of Novel Dual GIP and GLP-1 Receptor Agonist Tirzepatide on Biomarkers of Nonalcoholic Steatohepatitis in Patients With Type 2 Diabetes
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