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Reversibility, persistence, and progression of safrole-induced mouse liver lesions following cessation of exposure

Becerra-Diaz M, Song M, Heller N

When mitophagy is dysregulated, damaged mitochondria accumulate, resulting in mitochondrial DNA damage, ROS amplification, energetic collapse, and cardiomyocyte death

"We're all holding our breath a little bit," said Peter Koshland, who teaches clinical pharmacy at UC San Francisco, "and just hoping that nobody gets hurt."

Anything that potentially influences healing pathways, inflammation, or vascular factors deserves a thoughtful review

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