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While NO serves physiological signalling roles, its high diffusibility enables widespread oxidative and nitrosative damage to cellular components

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While the conventional therapeutic applications of GLP-1RAs have primarily focused on metabolic disorders, their multifaceted neuroprotective properties and anti-inflammatory mechanisms present a distinctive therapeutic opportunity for ophthalmic pathologies, potentially offering direct ocular benefits beyond systemic metabolic control

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Despite reports of melanoma, according to a study of social media posts the drug is often marketed as protecting against skin cancer