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Compared to the transvenous approach, intra-arterial injection can deliver cells directly into the renal artery and kidney through a femoral artery catheterization bypassing a clearance in the body, particularly in the pulmonary and splenic capillary network

It has been studied in scientific literature for its interactions with BDNF synthesis, serotonin/dopamine systems, and gene expression related to vascular and immune pathways

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