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Once in the cytosol acetyl-carnitine is converted to acetyl-CoA via the action of cytosolic CAT

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They don't establish that GLP-1s should be avoided - they establish that a musculoskeletal protection plan is a necessary component of responsible GLP-1 therapy

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By thoroughly investigating the systemic effects mediated by the carnitine pool, including its impacts on the liver, gut, kidney, muscle, heart, lung, and eye, we emphasize the importance of maintaining carnitine pool homeostasis for overall metabolic health and inter-organ metabolic cooperation

Sekar et al