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Its administration decreased levels of 4-hydroxynonenal (a product of lipid peroxidation) in patients with cardiomyopathy (Malig et al., 2016)

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To avoid collateral effects, more specific modulators of amino acids metabolism can be developed, through the use of monoclonal antibodies, mimetic peptides that activate receptors, proteolysis-targeting chimera degraders, and/or antisense nucleotides targeting genes (receptors, transporters, or enzymes) [252,253,254,255]